No specific amount of time. The way we design our recipes are to include foods shown to have certain benefits for certain conditions. Each of us are different and since the NutriBlasts are not like prescription medications it may take longer or shorter to notice the effects. In addition, it's always good to switch up your foods every now and then to get different nutrients. So, with all that being said - if you like it, maybe drink that one 2 times a week and include other cleansing recipes throughout the week!